Momentum gained from Iowa State’s 108-74 first-round win over Tennessee State is undermined by uncertainty over second-team All-American appearance joshua jefferson The Cyclones are preparing for a second-round game against the Kentucky Wildcats. Jefferson suffered an ankle injury in the opening minutes of the game against the Tigers and did not return. He is listed as questionable on the injury report. Without Jefferson, who averaged nearly 17 points per game, the Cyclones will be forced to rely more on their top-tier defense and outside shooting. Milan MomchilovicA point guard who currently shoots nearly 50% of his three-pointers Tamin Lipsey.
Kentucky earned a dramatic 89-84 overtime victory over Santa Clara on Sunday at Enterprise Center. Ortega Ove The midfielder dribbled the ball several times to beat the buzzer, forcing the team to enter overtime. under the head coach Mark Popethe Wildcats’ offense is hot and with Jefferson likely missing the game due to Iowa State, they will be at full strength for 40 minutes.
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To beat their opponents and advance to the Sweet 16 in a row, Kentucky must use their rebounding advantage against Iowa State, which struggled at times on the glass despite Jefferson being healthy. It won’t hurt that Pope’s men shot 51 percent from the field against Santa Clara.
This is the second meeting between these schools. Kentucky beat ISU 87-71 in that meeting. The winner advances to the Sweet 16 and plays a game with the winners of Tennessee and Virginia.
Let’s take a closer look at the second-round games, taking into account lineups, injuries, and other factors that impact lineups and overall scores.
We’ve got all the information and analysis you need to know ahead of the game, including the latest on how to catch the ball, odds Draft king Recent team performances, player statistics and of course our predictions to select the best bets for the match from our modeling tools and team of experts.
Game details and how to watch live: Iowa State vs. Kentucky
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date: Sunday, March 22, 2026
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Game Odds: Iowa State vs Kentucky
The latest odds as of Saturday are from Draft king:
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Money line: Iowa State Cyclones (-218), Kentucky Wildcats (+180)
Iowa State started this game at -5.5 and had a total score of 145.5.
Be sure to check it out Draft king Get all the latest game odds and player props for every game on this week’s NCAA basketball schedule!
Projected starting lineup: Iowa State vs. Kentucky
Iowa Cyclones
kentucky wildcats
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Key Stats, Trends and Insights: Iowa State vs. Kentucky
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Iowa State has an overall ATS record of 22-13 this season.
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Kentucky is 18-17 ATS overall this season
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Kentucky has won 18 of 35 games this season (18-17).
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OVER has won just 16 of Iowa State’s 35 games this season (16-19)
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Ortega Ove On Friday, he scored 35 points, grabbed eight rebounds and dished out seven assists in 43 minutes.
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Nate Hayes Scored 22 points off the bench for the Cyclones on Friday, including 4-5 from three-point range
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Our model calculates predictions for every moneyline, spread, and over/under for every game on the NCAA calendar based on data points such as recent performance, player matchups, trend information, and projected game totals.
Once the model has finished running, we place its predictions next to the game’s latest betting line to get a relative confidence level for each bet.
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Here are our model’s top bets for Sunday’s game between Iowa State and Kentucky:
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Money line: Rotoworld Betting Stays Away from Moneyline Betting
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spread: Rotoworld betting favors Kentucky +4.5
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All: Rotoworld betting favors game total over 145.5
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