In the 2-2 draw with Napoli, Wesley injured his left ankle after being roughly tackled by Amir Rahmani.
The former Flamengo man was forced to limp off the pitch and Roma’s medical staff immediately applied ice packs to the injured area.
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Over the next few hours, Rhythm Players will undergo tests to assess the extent of the injury, the report said.
The new touchline represents another big loss for Roma, who are already dealing with several absences at key points in the season.
The team is indeed awaiting a crucial match against Juventus, which is scheduled to take place at the Stadio Olimpico in two weeks and will be crucial for Roma’s season goals.
If Wesley’s injury is serious, it will be another blow to Gian Piero Gasperini’s side.
Roma, meanwhile, hope that Hermoso and Cone will be back for next Sunday’s game against Cremonese.
The Spaniard and Frenchman should be back in training this week and have been called up to face Nikola.