March Madness 2026, odds, betting: Best, worst NCAA tournament teams against the spread this season

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The 2026 NCAA Tournament is quickly approaching and March Madness is officially here, with the Final Four kicking off Tuesday night in Dayton, Ohio.

Will No. 1 overall seed — and betting favorite — Duke and superstar Cam Boozer upset the Nets? Is this the year Gonzaga makes another Final Four? Can Miami (Ohio), which is 31-1 and a 7.5-point underdog, win its first four games and advance to Friday?

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These are just a few of the many questions we look forward to getting answered over the next few weeks of competition. For betting purposes, though, it’s always instructive to know which teams have favored bettors so far this season, and which teams haven’t.

In a surprising move, the Penn Quakers became the college basketball team with the most money bettors cashed out this season as they defeated Yale 88-84 in overtime to win the Ivy League Championship thanks to an incredible 44-point performance by TJ Power.

[Enter Yahoo Bracket Mayhem now | Printable bracket]

Among the 68 teams in the 2026 NCAA Tournament, here are the five teams with the best and worst matchup distribution this season:

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The Five Best March Madness ATS Teams

The Five Worst March Madness ATS Teams

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