renew: As of 9:30 p.m., all lanes had reopened.
Jacksonville Fire Rescue tells Jax Action News that two adults with life-threatening injuries and two pediatric patients with non-life-threatening injuries were rescued from the scene.
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The Florida Highway Patrol reported the crash Sunday at 7 p.m. All northbound lanes of I-295E at Alta Drive were subsequently closed.
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Highway cameras on FL511 show an overturned vehicle and several emergency crews responding.
This story will be updated as more information becomes available.
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